Efficacy and safety of intravenous thrombolysis in elderly patients with acute cerebral infarction
International Journal of Surgical Research
江苏省响水县人民医院 江苏盐城 ;
分析高龄急性脑梗死静脉溶栓治疗的有效性和安全性。方法 本文一共纳入50例实验对象，均是2020年6月至2021年11月来我院诊治的高龄急性脑梗死患者，利用红绿双色球法进行分组，分为对照组（n=25，常规治疗）与研究组（n=25，静脉溶栓治疗）。对比分析两组的神经功能、日常生活能力以及血管内皮功能，统计两组的并发症。结果 在NIHSS评分与BI评分上，研究组优于对照组（P＜0.05）。在血浆内皮素-1（ET-1）与一氧化氮（NO）上，研究组优于对照组（P＜0.05）。在并发症发生率上，两组差异不大（P＞0.05）。结论 静脉溶栓治疗高龄急性脑梗死患者的效果良好，临床可进一步推广运用。
Objective to analyze the efficacy and safety of intravenous thrombolysis in elderly patients with acute cerebral infarction. Methods a total of 50 experimental subjects were included in this paper. They were all elderly patients with acute cerebral infarction treated in our hospital from June 2020 to November 2021. They were divided into control group (n = 25, routine treatment) and study group (n = 25, intravenous thrombolytic treatment) by red and green double color ball method. The neurological function, activities of daily living and vascular endothelial function of the two groups were compared and analyzed, and the complications of the two groups were counted. Results in NIHSS score and Bi score, the study group was better than the control group (P < 0.05). In plasma endothelin-1 (ET-1) and nitric oxide (no), the study group was better than the control group (P < 0.05). There was no significant difference in the incidence of complications between the two groups (P > 0.05). Conclusion intravenous thrombolysis is effective in the treatment of elderly patients with acute cerebral infarction, which can be further popularized in clinic.
Old age; Acute cerebral infarction; Intravenous thrombolysis; Security