International Journal of Surgical Research

Objective To investigate the risk factors of multidrug resistant bacterial infection (MDR) in neurosurgery patients with pulmonary infection, so as to provide reference for clinical prevention and control and hospital infection prevention and control. Methods The clinical data of about 200 neurosurgery patients with pulmonary infection were collected in detail (from June 2020 to July 21, 20221). The patients were divided into the observation group (n=100) and the control group (n=100) according to the MDR bacteria detection results. In-depth analysis of the two pathogenic characteristics, for two patients with klebsiella pneumoniae, acinetobacter baumannii drug resistance differences were compared. Regression analysis was conducted to analyze the health factors of multiple drug resistant bacteria infection in neurosurgery patients with pulmonary infection. Results Compared with the control group, the antibiotic resistance rate of Klebsiella pneumoniae and Acinetobacter baumannii in the observation group was significantly higher (P<0.05). According to the qualified analysis, the multi drug resistant bacteria in neurosurgery combined with pulmonary infection mainly include hospitalization time over 30 days, age over 65 years, malnutrition, and use of non restricted antibiotics for more than 7 days. Conclusion In the course of clinical treatment of neurosurgery patients with pulmonary infection, MDR infection is very likely to occur if there are bedridden, malnutrition or anemia, hospital stay more than 30 days, old age, and antibacterial drug use more than 7 days. Therefore, screening should be carried out regularly for patients with high risk factors, and multiple measures should be taken for comprehensive intervention, so as to effectively prevent MDR infection in the hospital.

neurosurgery; Lung infection; MDR bacteria; Risk factors